One pill to stop the flu from spreading at home? a new trial puts sebaloxavir to the test.
NCT ID NCT07730346
First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time
Summary
This phase 3 trial is testing whether a single dose of the antiviral drug sebaloxavir marboxil can prevent influenza in household members (ages 2 and up) who live with someone recently diagnosed with the flu. Participants are randomly assigned to receive either the drug or a placebo, and researchers track who develops a confirmed flu infection with symptoms. The goal is to see if this one-time treatment can safely stop the virus from spreading within a home.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a single dose of an antiviral drug called sebaloxavir marboxil, given as tablets or oral suspension
- What this could lead to
- If it works, this could offer a simple, one-dose way to stop the flu from spreading within a household after someone gets sick.
- What could go wrong
- This is an early-phase 3 trial, so the drug may not prove effective or safe enough for prevention. Side effects are possible, and results in a controlled trial may not reflect real-world use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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China Japan friendship hospital
Beijing, Beijing Municipality, 100029, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.