Oxygen-Guided transfusions could cut unnecessary blood use in ICUs

NCT ID NCT07509203

Not yet recruiting Knowledge-focused Sponsor: Semmelweis University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether measuring oxygen levels in the blood (ScvO2) can help doctors decide more precisely when to give red blood cell transfusions to critically ill patients with anemia. The goal is to reduce unnecessary transfusions and their complications. Researchers will compare this oxygen-guided approach to the usual method where doctors decide based on their own judgment. The trial plans to enroll 600 ICU patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: central venous saturation (ScvO2) measurement
What this could lead to: If successful, this could lead to a more personalized and safer way to decide when ICU patients need a blood transfusion, reducing unnecessary transfusions and their risks.
What could go wrong: This is an early-stage protocol study (not yet recruiting) with 600 participants. The approach may not prove better than current practice, and results may not apply to all ICU patients.

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Conditions

The condition(s) this trial relates to.

anemia Critical Illness

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANAEMIA

Contacts and locations

Locations

North-Pest Central Hospital- Hungarian Defense Forces Medical Center, Department of Anaesthesiology and Intensive Therapy

Budapest, 1134, Hungary
Semmelweis University, Department of Intensive Therapy

Budapest, 1082, Hungary

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