New hope for Hard-to-Treat depression? schema therapy put to the test
NCT ID NCT05833087
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study tests a type of talk therapy called schema therapy for people whose depression has lasted a long time or hasn't gotten better with medication. 129 participants will either get 30 sessions of schema therapy or standard psychotherapy. The goal is to see if schema therapy works better for easing depression symptoms and related problems.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
schema therapy (a type of psychotherapy)
What this could lead to
If it works, this could give people with long-lasting, hard-to-treat depression a new, more effective therapy option.
What could go wrong
This is a relatively small trial (129 people) and results may not apply to everyone. The therapy is time-intensive (30 sessions), and it may not work better than existing treatments.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Local Psychiatry Odense, Region of Southern Denmark Psychiatry
RECRUITINGOdense, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Outpatient clinic for Affective Disorders, Frederiksberg, Capital Region of Denmark Psychiatry
NOT_YET_RECRUITINGCopenhagen, 2000, Denmark
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Psychiatric Unit Odense-Svendborg, Southern Region of Denmark Psychiatry
NOT_YET_RECRUITINGSvendborg, 5700, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Psychotherapeutic Clinic Frederiksberg, Psychiatric Center Copenhagen, Mental Health Services, Capital Region of Denmark
RECRUITINGFrederiksberg, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Psychotherapeutic Out-patient Clinic, Psychiatric Center Ballerup, Mental Health Services, Capital Region of Denmark
RECRUITINGBallerup Municipality, 2750, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Psychotherapeutic Out-patient Clinic, Psychiatric Center Copenhagen/Nannasgade, Mental Health Services, Capital Region of Denmark
RECRUITINGCopenhagen, 2200, Denmark
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••