Gut bacteria supplement studied for arthritis relief

This small pilot study tested whether a short-chain fatty acid (SCFA) supplement could change gut bacteria and immune responses in people with rheumatoid arthritis who did not get enough help from methotrexate. About 20 participants took the supplement for one month, with an optional second month. Researchers collected stool, urine, and blood samples to measure changes in gut microbiome and immune cells. The goal was to gather early data, not to prove a treatment effect.