Engineered immune cells take on lupus and vasculitis in early trial
NCT ID NCT06294236
First seen Dec 18, 2025 · Last updated Jun 14, 2026 · Updated 27 times
Summary
This early-phase study tests a new treatment called SC291 for people with severe lupus or vasculitis that hasn't responded to standard therapies. SC291 uses donor immune cells engineered to target and destroy faulty immune cells driving the disease. The main goal is to check safety and how well the body tolerates the treatment, with early signs of effectiveness also being measured.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Emory University
Atlanta, Georgia, 30322, United States
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Johns Hopkins Hospital
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Swedish Medical Center
Seattle, Washington, 98122, United States
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University of Colorado
Aurora, Colorado, 80045, United States
Conditions
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