First test of 'Universal' Cancer-Fighting cells in patients

NCT ID NCT05878184

Summary

This is a first-in-human study to test the safety and early effects of a new type of cancer treatment called SC291. It is for adults with certain B-cell blood cancers (like non-Hodgkin lymphoma or chronic lymphocytic leukemia) that have come back or not responded to at least two prior treatments. SC291 is an 'off-the-shelf' CAR T-cell therapy, made from donor cells, designed to avoid rejection by the patient's immune system.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Karmanos Cancer Institute

    Detroit, Michigan, 48201, United States

  • Linear Clinical Research Ltd

    Nedlands, Western Australia, 6009, Australia

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Northside Hospital

    Atlanta, Georgia, 30342, United States

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Royal Adelaide Hospital

    Adelaide, South Australia, 5000, Australia

  • Stanford Cancer Institute

    Palo Alto, California, 94304, United States

  • University of Kansas Medical Center

    Fairway, Kansas, 66205, United States

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.