New combo attack on kidney cancer: radiation plus two drugs

NCT ID NCT07470840

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial will test a combination of precise radiation (SBRT) and two drugs—anlotinib (which cuts off tumor blood supply) and bemarituzumab (which boosts the immune system)—in 27 people with advanced kidney cancer that cannot be surgically removed. The main goal is to see how many patients' tumors shrink significantly. The study is not yet recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Anlotinib (oral anti-angiogenic drug) and bemarituzumab (intravenous immunotherapy), plus stereotactic body radiation therapy (SBRT)
What this could lead to
If successful, this combination could offer a new treatment option that shrinks tumors and delays progression in advanced kidney cancer.
What could go wrong
This is a small, early-phase trial (27 people) with no results yet. The combination may cause significant side effects, and the benefit may not be confirmed in larger studies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fujian Cancer Hospital

    Fuzhou, Fujian, 350014, China

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