New hope for advanced kidney cancer when first treatments stop working

NCT ID NCT03945773

Summary

This study tested the drug cabozantinib as a second treatment for people with advanced kidney cancer that had spread and worsened after their first treatment with immunotherapy. The goal was to see if the drug could shrink tumors and control the disease. It involved 127 adults and measured how well and for how long the treatment worked, along with its side effects.

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Contacts and locations

Locations

  • Beatson West of Scotland Cancer Centre

    Glasgow, G12 0YN, United Kingdom

  • CHRU Besançon

    Besançon, 25000, France

  • CHU Strasbourg

    Strasbourg, 67091, France

  • CHU de Nîmes - Institut de Cancérologie du Gard

    Nîmes, 30029, France

  • Caritas Krankenhaus St.Josef Klinik für Urologie

    Regensburg, D-93053, Germany

  • Centre Hospitalier Lyon Sud

    Pierre-Bénite, 69495, France

  • Centre Hospitalier Universitaire Vaudois

    Lausanne, 1011, Switzerland

  • Centre Jean Perrin

    Clermont-Ferrand, 63011, France

  • Centre Léon Bérard

    Lyon, 69008, France

  • Gustave Roussy

    Villejuif, 94805, France

  • Hospital Lucus Augusti

    Lugo, 27003, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital de La Santa Creu i Sant Pau

    Barcelona, 08041, Spain

  • Institut Claudius Régaud

    Toulouse, 31059, France

  • Institut Mutualiste Montsouris

    Paris, 75014, France

  • Institut Paoli Calmettes

    Marseille, 13009, France

  • Institut de Cancérologie de Lorraine

    Nancy, 54511, France

  • Institut de Cancérologie de l'Ouest

    Saint-Herblain, 44800, France

  • Kantonsspital St. Gallen

    Sankt Gallen, 9007, Switzerland

  • Klinikum Der Friedrich-Schiller-Universitaet Jena

    Jena, D-07747, Germany

  • Leiden University Medical Center

    Leiden, 2300-RC, Netherlands

  • M.D. Anderson Center Madrid

    Madrid, 28033, Spain

  • Maxima Medisch Centrum

    Eindhoven, 5604 DB, Netherlands

  • Medizinische Hochschule Hannover

    Hanover, D-30625, Germany

  • Mount Vernon Hospital

    Northwood, HA6 2RN, United Kingdom

  • Otto-von-Guericke-Universität University hospital Magdeburg

    Magdeburg, D-39120, Germany

  • Royal Cornwall Hospital (RCH) - Sunrise Centre

    Truro, TR1 3LJ, United Kingdom

  • SALK - Salzburger Landesklinik

    Salzburg, A-5020, Austria

  • The Christie NHS Foundation Trust

    Manchester, M20 4BX, United Kingdom

  • The Netherlands Cancer Institute - Oncology

    Amsterdam, 1066 CX, Netherlands

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

  • University Cancer Center Hamburg Eppendorf

    Hamburg, d-20246, Germany

  • University Hospital Carl Gustav Carus Dresden

    Dresden, D-1307, Germany

  • University Hospital Tuebingen

    Tübingen, D-72076, Germany

  • University, Hospital Münster

    Münster, D-48149, Germany

  • Universitätsklinikum Essen

    Essen, D-45147, Germany

  • Universitätsklinikum Schleswig-Holstein

    Lübeck, D-23538, Germany

  • Universitätsmedzin Charité

    Berlin, D-10117, Germany

  • Universitätsspital Bern, Inselspital

    Bern, 3010, Switzerland

  • Western General Hospital - Edinburgh Cancer Centre

    Edinburgh, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.