New hope for Hard-to-Treat lung condition: drug targets inflammation

NCT ID NCT05679570

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 26 times

Summary

This study tests a drug called satralizumab in 20 adults with pulmonary arterial hypertension (PAH) who have high levels of the inflammatory marker IL-6 and haven't responded well to standard treatments. The main goal is to see if the drug improves blood flow in the lungs over 24 weeks. This is an early-phase trial focused on safety and effectiveness.

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Contacts and locations

Locations

  • Chiba University Hospital

    Chiba, 260-8677, Japan

  • Hokkaido University Hospital

    Sapporo, 060-8648, Japan

  • International University of Health and Welfare Mita Hospital

    Tokyo, 108-8329, Japan

  • Kagoshima University Hospital

    Kagoshima, Kagoshima-ken, 890-8520, Japan

  • Kobe University Hospital

    Kobe, 650-0017, Japan

  • Kurume University Hospital

    Kurume, 830-0011, Japan

  • Kyorin University Hospital

    Mitaka, 181-8611, Japan

  • Kyushu University Hospital

    Fukuoka, 812-8582, Japan

  • Nagoya University Hospital

    Nagoya, 466-8560, Japan

Conditions

Explore the condition pages connected to this study.