Bladder cancer vaccine trial shows promise without chemo

NCT ID NCT05241340

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study tests a new approach for people with muscle-invasive bladder cancer who cannot receive standard chemotherapy. The treatment combines an immunotherapy drug (sasanlimab) with targeted radiation to help the body's immune system fight the tumor before surgery. The goal is to see if this combination is safe and can lead to a complete response in the removed bladder tissue.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77006, United States

Conditions

Explore the condition pages connected to this study.