Scientists deliberately infect volunteers with omicron to Fine-Tune future studies

NCT ID NCT06478420

First seen Nov 18, 2025 · Last updated May 16, 2026 · Updated 27 times

Summary

This study gives healthy adults aged 18-40 who have already had a COVID vaccine or prior infection a small dose of the Omicron BA.5 virus through the nose. The goal is to find the safest dose that causes a mild, controlled infection in about half to three-quarters of participants. Researchers will monitor symptoms and viral levels closely to improve future COVID research. This is not a treatment or cure—it helps scientists better understand how the virus behaves in immune-experienced people.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Centre for Clinical Vaccinology and Tropical Medicine

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

Conditions

Explore the condition pages connected to this study.