New hope for kids with rare arthritis: sarilumab Dose-Finding trial launches

NCT ID NCT02991469

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 24 times

Summary

This study is for children aged 1 to 17 with systemic juvenile idiopathic arthritis (sJIA), a rare and serious form of arthritis that causes joint swelling and fevers. The purpose is to find the best dose of the drug sarilumab, which helps control inflammation. Researchers will monitor how the drug moves through the body, its safety, and how well it reduces disease activity over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Investigational Site Number : 0320004

    RECRUITING

    San Miguel de Tucumán, Tucumán Province, T4000, Argentina

  • Investigational Site Number : 0320005

    RECRUITING

    Buenos Aires, 1023, Argentina

  • Investigational Site Number : 1240110

    RECRUITING

    Calgary, Alberta, T3B 6A9, Canada

  • Investigational Site Number : 2460040

    RECRUITING

    Helsinki, 00029, Finland

  • Investigational Site Number : 2500040

    RECRUITING

    Paris, 75015, France

  • Investigational Site Number : 2500041

    RECRUITING

    Bron, 69500, France

  • Investigational Site Number : 2500042

    RECRUITING

    Montpellier, 34295, France

  • Investigational Site Number : 2760060

    RECRUITING

    Sankt Augustin, 53757, Germany

  • Investigational Site Number : 2760062

    RECRUITING

    Hamburg, 22081, Germany

  • Investigational Site Number : 2760063

    COMPLETED

    Sendenhorst, 48324, Germany

  • Investigational Site Number : 2760064

    RECRUITING

    Berlin, 13125, Germany

  • Investigational Site Number : 2760065

    RECRUITING

    Berlin, 13353, Germany

  • Investigational Site Number : 3000001

    RECRUITING

    Athens, 115 27, Greece

  • Investigational Site Number : 3000002

    RECRUITING

    Thessaloniki, 546 42, Greece

  • Investigational Site Number : 3720001

    RECRUITING

    Crumlin, Dublin, D12 N512, Ireland

  • Investigational Site Number : 3800051

    RECRUITING

    Genoa, Genova, 16147, Italy

  • Investigational Site Number : 3800052

    RECRUITING

    Rome, Roma, 00165, Italy

  • Investigational Site Number : 3800054

    RECRUITING

    Milan, Milano, 20122, Italy

  • Investigational Site Number : 6430001

    COMPLETED

    Moscow, 115522, Russia

  • Investigational Site Number : 6430062

    COMPLETED

    Moscow, 117997, Russia

  • Investigational Site Number : 6430063

    COMPLETED

    Moscow, 119991, Russia

  • Investigational Site Number : 6430065

    COMPLETED

    Ufa, 450083, Russia

  • Investigational Site Number : 7240050

    RECRUITING

    Esplugues de Llobregat, Barcelona [Barcelona], 08950, Spain

  • Investigational Site Number : 7240051

    RECRUITING

    Valencia, 46026, Spain

  • Investigational Site Number : 7240053

    RECRUITING

    Madrid, 28009, Spain

  • Investigational Site Number : 7240054

    RECRUITING

    Málaga, 29010, Spain

  • Investigational Site Number : 7240055

    RECRUITING

    Barcelona, Barcelona [Barcelona], 08035, Spain

  • Investigational Site Number : 7240056

    RECRUITING

    Madrid, 28010, Spain

  • Investigational Site Number : 8260031

    COMPLETED

    London, London, City of, WC1N 3JH, United Kingdom

  • Investigational Site Number : 8260033

    COMPLETED

    Liverpool, L12 2AP, United Kingdom

  • Investigational Site Number : 8260034

    RECRUITING

    Leeds, LS1 3EX, United Kingdom

Conditions

Explore the condition pages connected to this study.