New drug aims to unclog lungs in chronic bronchiectasis patients

NCT ID NCT07547436

First seen Jun 27, 2026 · Last updated Jul 30, 2026 · Updated 2 times

Summary

This study tests an experimental drug called SAR445399 in 70 adults aged 18-80 with non-cystic fibrosis bronchiectasis, a lung condition causing mucus buildup and infections. Participants receive either the drug or a placebo for 24 weeks to see if it reduces mucus plugs seen on CT scans. The goal is to improve breathing and reduce flare-ups.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Advanced Pulmonary Research Institute- Site Number : 8400001

    Loxahatchee Groves, Florida, 33470, United States

  • Clinical Research Associates of Central Pennsylvania- Site Number : 8400006

    DuBois, Pennsylvania, 15801, United States

  • Hull and Hull Medical Specialists- Site Number : 8400002

    Plantation, Florida, 33324, United States

  • Pulmonary Associates - Phoenix - East McDowell Road- Site Number : 8400008

    Phoenix, Arizona, 85006, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.