New hope for Tough-to-Treat multiple myeloma?

NCT ID NCT04000282

First seen Nov 01, 2025 · Last updated Jun 14, 2026 · Updated 33 times

Summary

This early-stage study tested a new drug, SAR442085, in 37 adults with multiple myeloma that had returned or stopped responding to prior treatments. The main goals were to find the safest dose and see if the drug could shrink tumors. While the drug aims to control the disease, it is not a cure, and patients may need ongoing therapy.

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Contacts and locations

Locations

  • City of Hope Site Number : 8400002

    Duarte, California, 91010, United States

  • Dana Farber Cancer Institute Site Number : 8400003

    Boston, Massachusetts, 02115, United States

  • Froedtert Hospital & Medical College of Wisconsin Site Number : 8400004

    Milwaukee, Wisconsin, 53226, United States

  • Investigational Site Number : 1580001

    Taipei, 10002, Taiwan

  • Investigational Site Number : 2030001

    Prague, 12808, Czechia

  • Investigational Site Number : 2030002

    Brno, 62500, Czechia

  • Investigational Site Number : 2030003

    Ostrava - Poruba, 70852, Czechia

  • Investigational Site Number : 2500001

    Toulouse, 31059, France

  • Investigational Site Number : 3000001

    Athens, 11528, Greece

  • Investigational Site Number : 7240001

    Salamanca, Salamanca, 37007, Spain

  • Mayo Clinic of Rochester Site Number : 8400005

    Rochester, Minnesota, 55905, United States

  • UNC Chapel Hill Site Number : 8400006

    Chapel Hill, North Carolina, 27599, United States

Conditions

Explore the condition pages connected to this study.