Scientists hunt for genetic clues to rare bone and skin disease

NCT ID NCT07081880

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study aims to uncover the genetic and immune factors behind SAPHO syndrome, a rare chronic condition causing bone inflammation and skin issues. Researchers will collect DNA and cells from 100 adults diagnosed with SAPHO to compare their genetic makeup with the general population. The goal is to better understand what causes the disease and why it varies so much between patients, which could eventually lead to more accurate diagnosis and tailored treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this research could uncover genetic markers that help diagnose SAPHO syndrome more accurately and point toward more personalized treatments.

What could go wrong

This is an observational study, not a treatment trial. It may not lead directly to new therapies, and results may take years to translate into clinical practice.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

SAPHO syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Cochin

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Paris Saint Joseph

    RECRUITING

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••