Healthy volunteers help scientists test brain drug in early study

NCT ID NCT03771586

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 29 times

Summary

This early-stage study tested a single dose of the experimental drug SAGE-718 in 22 healthy adults. Researchers used a ketamine challenge to see how the drug affects brain electrical activity, safety, and how the body processes it. The goal was to gather information, not to treat any disease.

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Contacts and locations

Locations

  • Sage Investigational Site

    Long Beach, California, 90806, United States

  • Sage Investigational Site

    Berlin, New Jersey, 08009, United States

Conditions

Explore the condition pages connected to this study.