Experimental drug aims to slow Huntington's cognitive decline

NCT ID NCT05358821

Summary

This study tested whether an experimental drug called SAGE-718 could improve thinking skills in people with early Huntington's disease. For 28 days, 69 participants either received the drug or a placebo (inactive substance) in a double-blind trial where neither they nor the researchers knew who got which. The main goal was to see if the drug could help with cognitive tasks like memory, problem-solving, and emotional recognition compared to healthy volunteers.

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Contacts and locations

Locations

  • Sage Investigational Site

    Birmingham, Alabama, 35233, United States

  • Sage Investigational Site

    Los Alamitos, California, 90720, United States

  • Sage Investigational Site

    Englewood, Colorado, 80113, United States

  • Sage Investigational Site

    Washington D.C., District of Columbia, 20057, United States

  • Sage Investigational Site

    Boca Raton, Florida, 33431, United States

  • Sage Investigational Site

    Tampa, Florida, 33602, United States

  • Sage Investigational Site

    Chicago, Illinois, 60612, United States

  • Sage Investigational Site

    Baltimore, Maryland, 21218, United States

  • Sage Investigational Site

    New York, New York, 10027, United States

  • Sage Investigational Site

    Chapel Hill, North Carolina, 27599, United States

  • Sage Investigational Site

    Cincinnati, Ohio, 45221, United States

  • Sage Investigational Site

    Philadelphia, Pennsylvania, 19104, United States

  • Sage Investigational Site

    Houston, Texas, 77030, United States

  • Sage Investigational Site

    Montreal, H2X 3E4, Canada

Conditions

Explore the condition pages connected to this study.