Experimental combo targets Hard-to-Treat cancers in early safety trial

NCT ID NCT02617277

First seen Nov 17, 2025 · Last updated May 23, 2026 · Updated 23 times

Summary

This early-phase study tested the safety of combining two experimental drugs (AZD1775 and durvalumab) in 56 adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to identify side effects and determine safe dosing. This trial did not aim to cure the disease, but to gather information for future studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Denver, Colorado, 80218, United States

  • Research Site

    Sarasota, Florida, 34232, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.