Could a lupus drug help people with rare immune deficiency?
NCT ID NCT04097561
First seen Jan 05, 2026 · Last updated May 16, 2026 · Updated 20 times
Summary
This early-stage study tests whether belimumab, a drug used for lupus, is safe for people with idiopathic CD4 lymphopenia (ICL) — a rare condition where the body has too few CD4 immune cells, raising infection risk. About 20 adults aged 18-70 with ICL and autoantibodies will receive 8 doses of belimumab by IV over several months. The main goal is to check for side effects; researchers will also monitor immune cell counts to see if the drug has any helpful effects.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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