New combo drug may ease strain on heart in stiff heart failure

NCT ID NCT05991284

First seen Jan 05, 2026 · Last updated Apr 28, 2026 · Updated 15 times

Summary

This study looks at whether adding sacubitril-valsartan to standard care helps people with a type of heart failure where the heart pumps normally but is stiff, and also has a leaky mitral valve. About 84 adults will take the drug or continue usual treatment for six months. Researchers will measure changes in heart pressure, oxygen use, and symptoms to see if the drug improves heart function.

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Contacts and locations

Locations

  • Ziekenhuis Oost-Limburg

    Genk, 3600, Belgium

Conditions

Explore the condition pages connected to this study.