Could a monthly infusion slow Alzheimer's? new trial tests sabirnetug

NCT ID NCT06335173

Ongoing Disease control Sponsor: Acumen Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 25 times

Summary

This study tests a new drug called sabirnetug, given as a monthly IV infusion, to see if it can slow down memory loss and daily function decline in people with early Alzheimer's disease. About 542 participants will receive either the drug or a placebo. The goal is to measure changes in thinking skills and ability to perform daily tasks over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AMC Research

Matthews, North Carolina, 28105, United States
Abington Neurological Associates

Abington, Pennsylvania, 19001, United States
ActivMed Practices and Research

Portsmouth, New Hampshire, 03801, United States
Alzheimer's Research and Treatment Center - Stuart

Stuart, Florida, 34997, United States
Alzheimers Research and Treatment Center - Wellington

Wellington, Florida, 33414, United States
Aqualane Clinical Research

Naples, Florida, 34105-8522, United States
Boston Center for Memory

Newton, Massachusetts, 02459, United States
Bradenton Research Center

Bradenton, Florida, 34205, United States
Brain Matters Research

Delray Beach, Florida, 33445, United States
Cae Oroitu

Getxo, Spain
CenExel - Advanced Memory Research Institute of NJ

Toms River, New Jersey, 08755, United States
CenExel - California Neuroscience Research Medical Group, Inc (CNR)

Sherman Oaks, California, 91403-2131, United States
CenExel - iResearch Atlanta

Decatur, Georgia, 30030, United States
Charité - Universitaetsmedizin Berlin

Berlin, Germany
Charter Research - Lady Lake

The Villages, Florida, 32162, United States
Charter Research - Winter Park

Winter Park, Florida, 32792, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Columbus Memory Center

Columbus, Georgia, 31909, United States
Conquest Research

Winter Park, Florida, 32789, United States
Coral Clinical Research

Homestead, Florida, 33032, United States
Finlay Medical Research

Miami, Florida, 33126, United States
Fundacio ACE

Barcelona, Spain
Fundacion Neuropolis - Hospital Viamed Montecanal

Cuarte de Huerva, Zaragoza, Spain
Gadolin Research, LLC

Beaumont, Texas, 77702, United States
Gil Fernandez-Yera, MD, PA

Coral Gables, Florida, 33135, United States
Hattiesburg Clinic - Memory Center

Hattiesburg, Mississippi, 39401-7246, United States
Healthy Brain Research

Long Beach, California, 90804, United States
Hippocampe d/b/a Ottawa Memory Clinic

Ottawa, Ontario, Canada
Hospital Ruber

Madrid, Spain
Hospital Universitari General de catalunya

Sant Cugat del Vallès, Barcelona, Spain
Hospital Universitari i Politècnic La Fe

Valencia, Spain
Hospital Victoria Eugenia

Seville, Spain
Irvine Medical Research

Irvine, California, 92614, United States
JEM Research Institute

Atlantis, Florida, 33462, United States
K2 Medical Research - Tampa

Tampa, Florida, 33607, United States
K2 Medical Research - Villages

Lady Lake, Florida, 32159, United States
Kerwin Medical Center

Dallas, Texas, 75231, United States
Keystone Clinical Research

Norristown, Pennsylvania, 19462, United States
MoCA Research and Innovations

Greenfield Park, Quebec, Canada
Neuroclin Glasgow

Motherwell, Lanarkshire, United Kingdom
Neurological Associates of Albany

Albany, New York, 12208, United States
Neurology Center of North Orange County

Fullerton, California, 92835, United States
Neurology Clinic. P.C

Cordova, Tennessee, 38018, United States
Ocala Health - Family Care Specialists - Ocala I

Ocala, Florida, 34470, United States
Office of Jeffrey S. Ross, MD

Northbrook, Illinois, 60640, United States
Okanagan Clinical Trials

Kelowna, British Columbia, Canada
Panthera Bio-Partners - Preston

Preston, Lancashire, United Kingdom
Panthera Biopartners - Sheffield

Sheffield, Yorkshire, United Kingdom
Policlínica Gipuzkoa

Donostia / San Sebastian, Spain
Progressive Medical Research

Port Orange, Florida, 32127, United States
Re:Cognition Health - Bristol

Bristol, United Kingdom
Re:Cognition Health - Fairfax

Washington D.C., District of Columbia, 22031, United States
Re:Cognition Health - Guildford

Guildford, Surrey, United Kingdom
Re:Cognition Health - London

London, Greater London, United Kingdom
Re:Cognition Health - Winchester

Winchester, Hampshire, United Kingdom
Research Center for Clinical Studies, LLC

Norwalk, Connecticut, 06851-4903, United States
Rhode Island Mood and Memory

East Providence, Rhode Island, 02914, United States
Senior Adult Specialty Research

Austin, Texas, 78757, United States
St. Pancras Clinical Research Ltd.

London, Greater London, United Kingdom
Summit Research Network

Portland, Oregon, 97210, United States
Syrentis Clinical Research

Santa Ana, California, 92705, United States
Technical University of Munich, School of Medicine and Health, Klinikum rechts der Isar

Munich, Germany
The Alliance for Multispecialty Research LLC (AMR)

Knoxville, Tennessee, 37920-1511, United States
The Cognitive and Research Center of New Jersey

Springfield, New Jersey, 07081, United States
The Neurology Center of Southern California - Carlsbad

Carlsbad, California, 92011-4219, United States
Toronto Memory Program (TMP) (Neurology Research Inc.)

Toronto, Ontario, Canada
University Hospital of Cologne

Cologne, Germany
Zentralinstitut für seelische Gesundheit

Mannheim, Germany

Conditions

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ALZHEIMER DISEASE