New study may spare some breast cancer patients from chemotherapy
NCT ID NCT07391774
First seen Feb 06, 2026 · Last updated Jun 16, 2026 · Updated 19 times
Summary
This study tests whether hormone therapy plus a targeted drug (ribociclib) works as well as chemotherapy followed by the same hormone therapy for people with high-stage, estrogen-positive, HER2-negative breast cancer that has a low risk of coming back. About 1,978 postmenopausal women and men will be randomly assigned to one of the two treatment groups. The goal is to see if skipping chemotherapy can maintain cancer control while reducing side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Cancer Care Specialists of Illinois - Decatur
RECRUITINGDecatur, Illinois, 62526, United States
Contact
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Decatur Memorial Hospital
RECRUITINGDecatur, Illinois, 62526, United States
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Illinois CancerCare - Washington
RECRUITINGWashington, Illinois, 61571, United States
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Illinois CancerCare-Bloomington
RECRUITINGBloomington, Illinois, 61704, United States
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Illinois CancerCare-Canton
RECRUITINGCanton, Illinois, 61520, United States
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Illinois CancerCare-Carthage
RECRUITINGCarthage, Illinois, 62321, United States
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Illinois CancerCare-Eureka
RECRUITINGEureka, Illinois, 61530, United States
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Illinois CancerCare-Galesburg
RECRUITINGGalesburg, Illinois, 61401, United States
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Illinois CancerCare-Kewanee Clinic
RECRUITINGKewanee, Illinois, 61443, United States
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Illinois CancerCare-Macomb
RECRUITINGMacomb, Illinois, 61455, United States
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Illinois CancerCare-Ottawa Clinic
RECRUITINGOttawa, Illinois, 61350, United States
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Illinois CancerCare-Pekin
RECRUITINGPekin, Illinois, 61554, United States
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Illinois CancerCare-Peoria
RECRUITINGPeoria, Illinois, 61615, United States
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Illinois CancerCare-Peru
RECRUITINGPeru, Illinois, 61354, United States
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Illinois CancerCare-Princeton
RECRUITINGPrinceton, Illinois, 61356, United States
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SIH Cancer Institute
RECRUITINGCarterville, Illinois, 62918, United States
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Southern Illinois University School of Medicine
RECRUITINGSpringfield, Illinois, 62702, United States
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Conditions
Explore the condition pages connected to this study.