New drug combo takes on deadly breast cancer in small trial

NCT ID NCT02876302

First seen Jun 27, 2026 · Last updated Jul 24, 2026 · Updated 1 time

Summary

This study tests whether adding the drug ruxolitinib to standard chemotherapy can help treat triple-negative inflammatory breast cancer, a rare and aggressive form of breast cancer. About 23 adults with this diagnosis will receive the combination before surgery. The goal is to see if the drug can block a cancer-driving protein and improve the chance of having no cancer left at the time of surgery.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States