Biomarker-Guided drug shows promise in preventing deadly transplant complication

NCT ID NCT07025538

First seen Nov 12, 2025 · Last updated Apr 28, 2026 · Updated 24 times

Summary

This early-phase trial tests whether the drug ruxolitinib can prevent chronic graft-versus-host disease (cGVHD) in people who have had a stem cell transplant for blood cancer. Doctors use a blood test to find patients at high risk for cGVHD and then give them ruxolitinib to try to stop the disease before it starts. The study involves 42 adults and focuses on safety and how well the drug works at preventing cGVHD.

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Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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