New hope for stem cell patients: drug may stop debilitating chronic GVHD

NCT ID NCT07025538

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tests whether the drug ruxolitinib can prevent chronic graft-versus-host disease (cGVHD) in 42 adults who had a stem cell transplant for blood cancer. Doctors use a blood test to find patients at high risk for cGVHD and then give them ruxolitinib to block the immune attack. The goal is to see if the drug is safe and can help patients avoid this serious complication.

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Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm chronic graft versus host disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact