New hope for kids battling dangerous transplant complication

NCT ID NCT03774082

Summary

This study tested whether adding the drug ruxolitinib to standard steroid treatment could help children with moderate to severe chronic graft vs host disease (cGvHD). cGvHD is a serious complication where donor immune cells attack the patient's body after a stem cell transplant. The trial enrolled 46 children and teenagers to see if the combination was safe and effective at controlling the disease.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GRAFT VS HOST DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Novartis Investigative Site

    São Paulo, 04039 001, Brazil

  • Novartis Investigative Site

    Toronto, Ontario, M5G 1X8, Canada

  • Novartis Investigative Site

    Prague, 150 06, Czechia

  • Novartis Investigative Site

    Tamil Nadu, Chennai, 600035, India

  • Novartis Investigative Site

    Pune, Maharashtra, 411004, India

  • Novartis Investigative Site

    Bangalore, 560099, India

  • Novartis Investigative Site

    Delhi, 110 085, India

  • Novartis Investigative Site

    Roma, RM, 00165, Italy

  • Novartis Investigative Site

    Nagoya, Aichi-ken, 466 8560, Japan

  • Novartis Investigative Site

    Saitama, 330 8777, Japan

  • Novartis Investigative Site

    Saint Petersburg, 197022, Russia

  • Novartis Investigative Site

    Bratislava, 833 40, Slovakia

  • Novartis Investigative Site

    Seoul, 03080, South Korea

  • Novartis Investigative Site

    Seoul, 05505, South Korea

  • Novartis Investigative Site

    Barcelona, Catalonia, 08035, Spain

  • Novartis Investigative Site

    Zurich, CH - 8032, Switzerland

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

  • Novartis Investigative Site

    Bangkok, 10400, Thailand

  • Novartis Investigative Site

    Adana, 1330, Turkey (Türkiye)

  • Novartis Investigative Site

    Antalya, 07000, Turkey (Türkiye)

  • Novartis Investigative Site

    Antalya, 07070, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.