New drug hope for dangerous immune overreaction after CAR-T cancer treatment

NCT ID NCT07424222

First seen Feb 22, 2026 · Last updated May 14, 2026 · Updated 13 times

Summary

This early study tests the drug ruxolitinib in 16 adults who develop a severe inflammatory condition called IEC-HS after CAR-T therapy. The goal is to see if the drug is safe and can control the inflammation. Participants take the drug twice daily for up to 8 weeks. This is a small pilot study, not a cure, but aims to manage a serious complication.

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Conditions

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