New drug combo aims to prevent deadly transplant complication in kids
NCT ID NCT06128070
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 28 times
Summary
This study tests whether adding the drug ruxolitinib to the standard anti-rejection drugs tacrolimus and methotrexate can better prevent graft-versus-host disease (GVHD) in children and young adults (ages 2-22) receiving a bone marrow transplant for blood cancers like leukemia. GVHD occurs when donor cells attack the patient's body. The trial will enroll 40 participants and monitor side effects and how well the drug combination works. Participants will still need lifelong immune-suppressing medication after transplant.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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