New hope for lung damage after transplant: drug trial shows promise

NCT ID NCT03674047

Ongoing Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Nov 10, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests the drug ruxolitinib for people who developed a lung condition called Bronchiolitis Obliterans Syndrome after a stem cell transplant. The goal is to see if the drug can improve lung function and stop the disease from getting worse. About 50 participants are enrolled in this phase 2 trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

City of Hope Cancer Center

Duarte, California, 91010, United States
Cleveland Clinic

Cleveland, Ohio, 44195, United States
Fred Hutchinson Cancer Center

Seattle, Washington, 98109, United States
H. Lee Moffitt Cancer Center

Tampa, Florida, 33612, United States
Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
Massachusetts General Hospital

Boston, Massachusetts, 02114, United States
Medical College of Wisconsin

Milwaukee, Wisconsin, 53226, United States

Conditions

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OTHER CANCER