New cream could ease painful skin bumps for HS sufferers

NCT ID NCT06959225

Recruiting now Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 22 times

Summary

This study tests a cream called ruxolitinib for people with mild to moderate hidradenitis suppurativa (HS), a condition that causes painful bumps under the skin. About 550 adults with HS for at least 6 months will apply the cream or a placebo twice daily. The main goal is to see if the cream reduces the number of inflamed bumps by at least 75% without worsening other symptoms.

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Contacts and locations

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Study contacts

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Locations

Investigative Site BG002
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Sofia, 01407, Bulgaria
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Sofia, 01463, Bulgaria
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Richmond Hill, Ontario, L4B 1L1, Canada
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Peterborough, Ontario, K9J 5K2, Canada
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Calgary, Alberta, T3E 0B2, Canada
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Calgary, Alberta, T2J 7E1, Canada
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Toronto, Ontario, M4E 1R7, Canada
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Waterloo, Ontario, N2J 1C4, Canada
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Toronto, Ontario, M3B 0A7, Canada
Investigative Site CA008
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Sherbrooke, Quebec, J1G 1X9, Canada
Investigative Site CA009
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Ottawa, Ontario, K1K 4L2, Canada
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Dresden, 01307, Germany
Investigative Site DE002
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Bochum, 44791, Germany
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Erlangen, 91054, Germany
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Darmstadt, 64283, Germany
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Berlin, 13595, Germany
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Berlin, 10117, Germany
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Hamburg, 20246, Germany
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Lübeck, 23538, Germany
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Madrid, 28009, Spain
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Madrid, 28040, Spain
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Barcelona, 08003, Spain
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Alicante, 03010, Spain
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Badalona, 08916, Spain
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Paris, 75010, France
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Bordeaux, 33000, France
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Nice, 06200, France
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Nantes, 44093, France
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Brest, 29609, France
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Catania, 95123, Italy
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Rozzano, 20089, Italy
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Milan, 20122, Italy
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Roma, 00144, Italy
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Cona, 44124, Italy
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Roma, 00137, Italy
Investigative Site IT007
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Naples, 80131, Italy
Investigative Site IT008
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Torino, 10126, Italy
Investigative Site IT009
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Florence, 50122, Italy
Investigative Site PL001
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Warsaw, 02-962, Poland
Investigative Site PL002
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Lodz, 90-436, Poland
Investigative Site PL003
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Torun, 87-100, Poland
Investigative Site PL004
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Wroclaw, 54-239, Poland
Investigative Site US001
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Bowling Green, Kentucky, 42104, United States
Investigative Site US002
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Fayetteville, Arkansas, 72703, United States
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Boston, Massachusetts, 02115, United States
Investigative Site US004
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Laguna Niguel, California, 92677, United States
Investigative Site US006
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Minneapolis, Minnesota, 55455, United States
Investigative Site US007
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Los Angeles, California, 90033, United States
Investigative Site US008
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Columbus, Ohio, 43230, United States
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Quincy, Massachusetts, 02169, United States
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San Antonio, Texas, 78213, United States
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Plano, Texas, 75025, United States
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San Diego, California, 92103, United States
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Chapel Hill, North Carolina, 27516, United States
Investigative Site US015
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Bexley, Ohio, 43209, United States
Investigative Site US016
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Miami, Florida, 33142, United States
Investigative Site US017
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New York, New York, 10023, United States
Investigative Site US018
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New York, New York, 10003, United States
Investigative Site US019
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Marietta, Georgia, 30060, United States
Investigative Site US020
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Phoenix, Arizona, 85008, United States
Investigative Site US021
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New Brighton, Minnesota, 55112, United States
Investigative Site US022
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Louisville, Kentucky, 40241, United States
Investigative Site US023
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Rochester, New York, 14623, United States
Investigative Site US024
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Charleston, South Carolina, 29425, United States
Investigative Site US025
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Fargo, North Dakota, 58103, United States
Investigative Site US026
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Chicago, Illinois, 60657, United States
Investigative Site US027
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Sanford, Florida, 32771, United States
Investigative Site US028
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Fort Myers, Florida, 33912, United States
Investigative Site US029
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Tampa, Florida, 33609, United States
Investigative Site US030
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Boston, Massachusetts, 02215, United States
Investigative Site US031
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Mason, Ohio, 45040, United States
Investigative Site US032
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Frisco, Texas, 75033, United States
Investigative Site US033
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Scottsdale, Arizona, 85259, United States
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New City, New York, 10956, United States
Investigative Site US035
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El Paso, Texas, 79902, United States
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Saint Joseph, Missouri, 64506, United States
Investigative Site US037
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Murray, Utah, 84107, United States
Investigative Site US038
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San Diego, California, 92121, United States
Investigative Site US039
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Ogden, Utah, 84405, United States
Investigative Site US040
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Layton, Utah, 84041, United States
Investigative Site US041
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Myrtle Beach, South Carolina, 29788, United States
Investigative Site US043
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Danville, Pennsylvania, 17822, United States
Investigative Site US044
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Cincinnati, Ohio, 45219, United States
Investigative Site US045
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Boynton Beach, Florida, 33437, United States
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Glenn Dale, Maryland, 20769, United States
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Nashville, Tennessee, 37215, United States
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Oklahoma City, Oklahoma, 73118, United States
Investigative Site US049
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Clarksville, Indiana, 47129, United States
Investigative Site US050
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Baton Rouge, Louisiana, 70809, United States
Investigative Site US051
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Novi, Michigan, 48377, United States
Investigative Site US052
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West Lafayette, Indiana, 47906, United States
Investigative Site US053
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Atlanta, Georgia, 30331, United States
Investigative Site US054
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Tempe, Arizona, 85282, United States
Investigative Site US055
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Brea, California, 92821, United States
Investigative Site US056
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Philadelphia, Pennsylvania, 19107, United States
Investigative Site US057
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Sweetwater, Florida, 33172, United States
Investigative Site US058
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Seattle, Washington, 98195, United States
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Aurora, Colorado, 80045, United States
Investigative Site US060
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San Diego, California, 92120, United States
Investigative Site US061
NOT_YET_RECRUITING

Atlanta, Georgia, 30322, United States
Investigative Site US062
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Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.

HIDRADENITIS SUPPURATIVA