Promising combo study halted early: hope for advanced blood cancer patients

NCT ID NCT03878199

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 26 times

Summary

This study tested a combination of two drugs, ruxolitinib and CPX-351, in people with advanced myeloproliferative neoplasms (MPN), a type of blood cancer that has progressed. The goal was to find the best dose and see if the combination worked better than CPX-351 alone. Only 12 people took part before the study was stopped early. The results may still help researchers understand how to treat these aggressive cancers.

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Contacts and locations

Locations

  • OHSU

    Portland, Oregon, 97239, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Simmons Cancer Center

    Dallas, Texas, 75390, United States

Conditions

Explore the condition pages connected to this study.