New combo therapy aims to make bone marrow transplants safer for older blood cancer patients
NCT ID NCT07228624
First seen Nov 15, 2025 · Last updated May 15, 2026 · Updated 17 times
Summary
This study tests whether adding the drug ruxolitinib to standard transplant care can prevent a serious side effect called graft-versus-host disease (GVHD) in older adults with myelofibrosis or related blood cancers. About 50 participants will receive ruxolitinib before, during, and after a donor stem cell transplant, along with usual anti-rejection medicines. The goal is to see if this approach reduces severe GVHD and improves recovery without increasing risks.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fred Hutch/University of Washington Cancer Consortium
RECRUITINGSeattle, Washington, 98109, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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