New drug combo tested for tough-to-treat cancers

NCT ID NCT03448042

Summary

This early-stage study is testing the safety and dosing of a new drug called runimotamab. It is being given alone and in combination with an existing cancer drug, trastuzumab, to people with advanced HER2-positive cancers like breast or stomach cancer that have stopped responding to standard treatments. The main goal is to find a safe dose and see how the body processes the drug.

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Contacts and locations

Locations

  • ASST Grande Ospedale Metropolitano Niguarda - Presidio Ospedaliero Ospedale Niguarda Ca' Granda

    Milan, Lombardy, 20162, Italy

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Centre Léon Bérard

    Lyon, Rhône, 69008, France

  • China Medical University Hospital

    Taichung, 40447, Taiwan

  • Churchill Hospital

    Oxford, Oxfordshire, OX3 7LJ, United Kingdom

  • EDOG - Institut Bergonie - PPDS

    Bordeaux, Gironde, 33000, France

  • Grand Hopital de Charleroi asbl

    Charleroi, 6000, Belgium

  • Gustave Roussy

    Villejuif, Val-de-Marne, 94805, France

  • Het Nederlands Kanker Instituut Antoni Van Leeuwenhoek Ziekenhuis

    Amsterdam, 1066 CX, Netherlands

  • Hospital Clinico Universitario de Valencia

    Valencia, 46010, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Quironsalud Madrid

    Pozuelo de Alarcón, Madrid, 28223, Spain

  • Institut Claudius Regaud

    Toulouse, 31059, France

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10017, United States

  • National Cancer Center East

    Chiba, 277-8577, Japan

  • National Cancer Centre

    Singapore, 168583, Singapore

  • National Taiwan University Hospital

    Taipei, 10048, Taiwan

  • Peter MacCallum Cancer Centre

    Melbourne, Victoria, 3000, Australia

  • Princess Margaret Hospital

    Toronto, Ontario, M5G 2M9, Canada

  • Rigshospitalet-Blegdamsvej 9

    Copenhagen, 2100, Denmark

  • SCRI Oncology Partners

    Nashville, Tennessee, 37203, United States

  • START MADRID_Hospital Universiario Fundacion Jimenez Diaz

    Madrid, 28040, Spain

  • START MADRID_Hospital Universitario HM Sanchinarro - CIOCC - EDOS

    Madrid, 28050, Spain

  • Seoul National University Hospital

    Seoul, 110-744, South Korea

  • Washington University

    Saint Louis, Michigan, 63130, United States

  • Yale University

    New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.