Magnetic pulses to the brain: a new hope for stroke paralysis?

NCT ID NCT01855633

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This trial tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique that uses magnetic pulses to stimulate specific brain areas, can improve motor recovery in people with hemiplegia after a stroke. Researchers will compare two types of theta burst stimulation (traditional and modified) against a sham (placebo) treatment. Participants, who must have stroke-related weakness and be at least two weeks past their stroke, will receive five days of stimulation. The main measure is a keyboard tapping test, which assesses hand speed and dexterity before and after the intervention.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Repetitive transcranial magnetic stimulation (rTMS) using theta burst stimulation (TBS), delivered as traditional TBS, modified TBS, or sham (placebo) stimulation.
What this could lead to
If effective, rTMS could offer a non-invasive way to boost motor recovery after stroke, helping patients regain hand and arm function when standard rehabilitation falls short.
What could go wrong
This is a small, early-stage trial with only 48 participants, and the treatment is given over just five days. Results may not generalize, and the sham comparison will help determine if any benefit is real or due to placebo.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 48 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2013

Expected to finish

Dec 2040

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * stroke patients with motor weakness * Medical research council (MRC) grade 0-4 * More than 2 weeks after stroke onset * Age 18 years and older * Able to provide consent for the protocol Exclusion Criteria: * History of previous symptomatic stroke * pregnant women * Persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded * Patients with history of seizure disorder or epilepsy * Subjects without the capacity to give informed consent

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • Dongtan Sacred Heart Hospital

    RECRUITING

    Hwaseong-si, Gyeonggi-do, 445-170, South Korea

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