Magnetic pulses to the brain: a new hope for stroke paralysis?
NCT ID NCT01855633
First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time
Summary
This trial tests whether repetitive transcranial magnetic stimulation (rTMS), a non-invasive technique that uses magnetic pulses to stimulate specific brain areas, can improve motor recovery in people with hemiplegia after a stroke. Researchers will compare two types of theta burst stimulation (traditional and modified) against a sham (placebo) treatment. Participants, who must have stroke-related weakness and be at least two weeks past their stroke, will receive five days of stimulation. The main measure is a keyboard tapping test, which assesses hand speed and dexterity before and after the intervention.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Repetitive transcranial magnetic stimulation (rTMS) using theta burst stimulation (TBS), delivered as traditional TBS, modified TBS, or sham (placebo) stimulation.
- What this could lead to
- If effective, rTMS could offer a non-invasive way to boost motor recovery after stroke, helping patients regain hand and arm function when standard rehabilitation falls short.
- What could go wrong
- This is a small, early-stage trial with only 48 participants, and the treatment is given over just five days. Results may not generalize, and the sham comparison will help determine if any benefit is real or due to placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 48 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Apr 2013
- Expected to finish
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Dec 2040
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * stroke patients with motor weakness * Medical research council (MRC) grade 0-4 * More than 2 weeks after stroke onset * Age 18 years and older * Able to provide consent for the protocol Exclusion Criteria: * History of previous symptomatic stroke * pregnant women * Persons with surgically or traumatically implanted foreign bodies such as a pacemaker, an implanted medication pump, a metal plate in the skull, or metal inside the skull or eyes (other than dental appliances or fillings), intracardiac lines that may pose a physical hazard during magnetic stimulation will also be excluded * Patients with history of seizure disorder or epilepsy * Subjects without the capacity to give informed consent
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Dongtan Sacred Heart Hospital
RECRUITINGHwaseong-si, Gyeonggi-do, 445-170, South Korea
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Other studies related to the condition(s) this trial covers.
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- Correlation of visual and motor deficits in stroke patients
- Pilot study on the effects induced by an electromyographic-controlled functional electrical stimulator (FitFES) for upper limb rehabilitation in post-stroke patients
- Brazilian version of a behavior change intervention to support healthy lifestyle adoption after stroke - iVIDAVC: protocol for a pilot randomized study
- Determination of efficacy of sustained motor contraction generated using StimWave peripheral nerve stimulator
- Can a PET tracer reveal hidden brain inflammation?