Could zapping the brain help older adults drink less and think sharper?

NCT ID NCT05896332

First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 33 times

Summary

This early-phase study tests whether a type of brain stimulation called rTMS can help older adults (ages 60-85) who have both alcohol use disorder and mild cognitive impairment. Participants receive 50 sessions of stimulation over one week. Researchers will measure changes in thinking skills, drinking behavior, and brain connectivity. The goal is to see if this approach can safely address both problems at once.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Medical Univeristy of South Carolina

    Charleston, South Carolina, 29425, United States

  • Medical University of South Carolina

    Charleston, South Carolina, 29425, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

repetitive transcranial magnetic stimulation (rTMS)

What this could lead to

If it works, this could point toward a non-drug treatment that helps older adults drink less and think more clearly.

What could go wrong

This is a very early, small phase 1 trial with only 35 people, so results may not apply widely. The treatment is intensive (50 sessions in one week) and may cause discomfort or side effects like headache or scalp pain.

Conditions

The condition(s) this trial relates to.

alcohol abuse Cognitive Dysfunction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.