Can a brain zap boost therapy for borderline personality disorder?

NCT ID NCT06259851

Ongoing Symptom relief Sponsor: Masarykova Univerzita Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study combines a type of brain stimulation called rTMS with dialectical behavioral therapy (DBT) to see if it helps people with borderline personality disorder more than therapy alone. Sixty participants will receive both treatments over several months. Researchers will measure changes in symptoms like impulsivity, emotional regulation, depression, and anxiety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS) combined with dialectical behavioral therapy (DBT)
What this could lead to: If it works, this could offer a more effective way to manage borderline personality disorder symptoms, reducing impulsivity and emotional suffering.
What could go wrong: This is a small, early-stage study with only 60 participants. The results may not apply to everyone, and the added benefit of rTMS over DBT alone is uncertain.

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Conditions

The condition(s) this trial relates to.

borderline personality disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BORDERLINE PERSONALITY DISORDER

Contacts and locations

Locations

Department of Psychiatry, University Hospital Brno and Faculty of Medicine, Masaryk University

Brno, 62500, Czechia

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