Modified virus attacks cancer cells in advanced tumor trial

NCT ID NCT03767348

Summary

This study is testing an experimental virus therapy called RP1, both alone and combined with an immunotherapy drug (nivolumab), for people with advanced solid tumors that have stopped responding to standard treatments. The trial aims to find the safest and most effective dose while measuring how well the treatment shrinks tumors in patients with specific types of skin cancer, lung cancer, and other solid tumors. Researchers are enrolling about 340 participants who have already tried and progressed on certain immunotherapies.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Banner MD Anderson Cancer Center

    Gilbert, Arizona, 85234, United States

  • Beatson West of Scotland Cancer Center

    Glasgow, Scotland, G12 0YN, United Kingdom

  • CHU Besancon - Hopital Jean Minjoz

    Besançon, 25000, France

  • CHU Dijon

    Dijon, 21079, France

  • CHU de Nice Hôpital l'Archet

    Nice, 06200, France

  • Carti Cancer Center

    Little Rock, Arkansas, 72205, United States

  • Centre Léon Bérard Lyon

    Lyon, 69373, France

  • Charité (Campus Benjamin Franklin)

    Berlin, 12203, Germany

  • Clinica Universitaria de Navarra

    Pamplona, 31008, Spain

  • Clínica Universidad de Navarra (Madrid)

    Madrid, 28027, Spain

  • Duke Cancer Center

    Durham, North Carolina, 27710, United States

  • Eccles Outpatient Care Center- Oncology Clinical Trials

    Murray, Utah, 84107, United States

  • Hospital Clinic Barcelona

    Barcelona, 08036, Spain

  • Hospital General Universitario de Valencia

    Valencia, 46014, Spain

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hospital Universitario Virgen de la Arrixaca

    Murcia, 30120, Spain

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hôpital Saint Louis APHP

    Paris, 75010, France

  • Institut Bergonié

    Bordeaux, 33076, France

  • Institut Gustave Roussy

    Villejuif, 94800, France

  • Intermountain Cancer Center- Saint George Cancer Center

    St. George, Utah, 84790, United States

  • James Graham Brown Cancer Center- University of Louisville

    Louisville, Kentucky, 40202, United States

  • MUSC Health

    Charleston, South Carolina, 29425, United States

  • Mayo Clinic

    Phoenix, Arizona, 85054, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • New York University Clinical Cancer Center

    New York, New York, 10016, United States

  • Oxford University Hospitals NHS Trust

    Oxford, Oxfordshire, United Kingdom

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Royal Marsden Hospital

    London, United Kingdom

  • Seattle Cancer Care Alliance- University of Washington

    Seattle, Washington, 98109, United States

  • Service de Dermatologie et Cancerologie Cutanee Hopital de la Timone

    Marseille, 13005, France

  • Southampton General Hospital

    Southampton, SO16 6YD, United Kingdom

  • Sylvester Comprehensive Cancer Center- University of Miami

    Miami, Florida, 33136, United States

  • The Clatterbridge Cancer Centre NHS Foundation Trust

    Bebington, Wirral, CH634JY, United Kingdom

  • The University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

  • UC San Diego

    La Jolla, California, 92093, United States

  • UCLA

    Los Angeles, California, 90095, United States

  • Uniklinik Marburg

    Marburg, 35043, Germany

  • University Hospital Essen, Klinik für Dermatologie

    Essen, 45147, Germany

  • University of Birmingham Alabama

    Birmingham, Alabama, 35294, United States

  • University of California, Irvine

    Orange, California, 92868, United States

  • University of California- San Francisco

    San Francisco, California, 94115, United States

  • University of Cincinnati Medical Center

    Cincinnati, Ohio, 45267, United States

  • University of Iowa-Cancer Center Research

    Iowa City, Iowa, 52242, United States

  • University of Kiel (UKSH), Dep. of Dermatology

    Kiel, 24105, Germany

  • University of Leeds- Teaching Hospital

    Leeds, England, LS97TF, United Kingdom

  • University of Rochester Medical Center

    Rochester, New York, 14642, United States

  • University of Southern California

    Los Angeles, California, 90033, United States

  • University of Wisconsin-Carbone Cancer Center

    Madison, Wisconsin, 53792, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

  • West Cancer Center

    Germantown, Tennessee, 38138, United States

Conditions

Explore the condition pages connected to this study.