New cancer pill tested in early trial – but study halted

NCT ID NCT06232408

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early-phase trial tested an oral drug called RP-1664 in people with advanced solid tumors that had stopped responding to standard treatments. The main goals were to find a safe dose and check for side effects. The study was terminated early, so full results may not be available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RP-1664 (an oral PLK4 inhibitor)

What this could lead to

If successful, this could point toward a new treatment option for people with advanced solid tumors that have not responded to other therapies.

What could go wrong

This was a very early Phase 1 trial with only 29 participants, and it was terminated, so results may not be available. The drug may not prove effective or safe in larger studies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ADVANCED SOLID TUMOR are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Participating Site 1004

    New York, New York, 10065, United States

  • Participating Site 1008

    New York, New York, 10032, United States

  • Participating Site 1012

    New Haven, Connecticut, 06519, United States

  • Participating Site 1025

    San Francisco, California, 94143, United States

  • Participating Site 4001

    Copenhagen, Denmark