Pee test could revolutionize HIV treatment adherence

NCT ID NCT06423612

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial tests whether a low-cost, point-of-care urine test can help people with HIV who are not virally suppressed stick to their antiretroviral therapy. Participants provide a urine sample that is immediately tested for the presence of the drug tenofovir. Based on the result, they receive enhanced counseling to improve adherence. The study aims to see if this real-time feedback leads to better viral suppression rates compared to standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
point-of-care urine test to measure adherence to antiretroviral therapy, with enhanced counseling based on results
What this could lead to
If effective, this simple and cheap urine test could help more people with HIV achieve viral suppression, improving health and reducing transmission.
What could go wrong
This is a single trial in one region, and the test only measures recent adherence. It may not work for everyone or in different settings.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Desmond Tutu HIV Foundation

    RECRUITING

    East London, South Africa

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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