Pee test could revolutionize HIV treatment adherence
NCT ID NCT06423612
First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time
Summary
This trial tests whether a low-cost, point-of-care urine test can help people with HIV who are not virally suppressed stick to their antiretroviral therapy. Participants provide a urine sample that is immediately tested for the presence of the drug tenofovir. Based on the result, they receive enhanced counseling to improve adherence. The study aims to see if this real-time feedback leads to better viral suppression rates compared to standard care.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- point-of-care urine test to measure adherence to antiretroviral therapy, with enhanced counseling based on results
- What this could lead to
- If effective, this simple and cheap urine test could help more people with HIV achieve viral suppression, improving health and reducing transmission.
- What could go wrong
- This is a single trial in one region, and the test only measures recent adherence. It may not work for everyone or in different settings.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Desmond Tutu HIV Foundation
RECRUITINGEast London, South Africa
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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