New hope for transplant patients with severe chronic GVHD
NCT ID NCT06682169
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug, rovadicitinib, for people with moderate to severe chronic graft-versus-host disease (cGVHD) after a stem cell transplant. Participants must have tried at least two prior treatments. The goal is to see if rovadicitinib improves symptoms better than standard care at 24 weeks.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC GRAFT VERSUS HOST DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Chinese Academy of Medical Sciences Hematology Hospital
NOT_YET_RECRUITINGTianjin, Tianjin Municipality, 300052, China
-
First Hospital of Jilin University
NOT_YET_RECRUITINGChangchun, Jilin, 130031, China
-
Fujian Medical University Union Hospital
NOT_YET_RECRUITINGFuzhou, Fujian, 350001, China
-
Guangzhou First People's Hospital The First People's Hospital Affiliated to Guangzhou Medical University
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510180, China
-
Henan Cancer Hospital
RECRUITINGZhenzhou, Henan, 450000, China
-
Henan Provincial People's Hospital
NOT_YET_RECRUITINGZhengzhou, Henan, 450003, China
-
Huai'an Second People's Hospital
NOT_YET_RECRUITINGHuai'an, Jiangsu, 223200, China
-
Jiangsu Province Hospital
NOT_YET_RECRUITINGNanjing, Jiangsu, 210029, China
-
Nanfang Hospital
NOT_YET_RECRUITINGGuangzhou, Guangdong, 510515, China
-
Peking University First Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100034, China
-
Peking University People's Hospital
NOT_YET_RECRUITINGBeijing, Beijing Municipality, 100044, China
-
Qilu Hospital of Shandong University
NOT_YET_RECRUITINGJinan, Shandong, 250012, China
-
Ruijin Hospital, Shanghai Jiaotong University School Of Medicine
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200025, China
-
Shanghai Jiao Tong University School of Medicine，Renji Hospital
NOT_YET_RECRUITINGShanghai, Shanghai Municipality, 200001, China
-
Shanxi Bethune Hospital
NOT_YET_RECRUITINGTaiyuan, Shanxi, 030032, China
-
Shanxi Provincial People's Hospital
NOT_YET_RECRUITINGXi’an, Shanxi, 710068, China
-
Sichuan Provincial People's Hospital
NOT_YET_RECRUITINGChengdu, Sichuan, 610072, China
-
Tai'an City Central Hospital
NOT_YET_RECRUITINGTai’an, Shandong, 271000, China
-
The 904 Hospital of the Joint Service Support Force of the People's Liberation Army of China
NOT_YET_RECRUITINGLanzhou, Gansu, 730050, China
-
The Affiliated Hospital of Guizhou Medical University
NOT_YET_RECRUITINGGuiyang, Guizhou, 550001, China
-
The Affiliated People's Hospital of Ningbo University
NOT_YET_RECRUITINGNingbo, Zhejiang, 315040, China
-
The First Affiliated Hospital of Guangxi Medical University
NOT_YET_RECRUITINGNanning, Guangxi, 530021, China
-
The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, Jiangxi, 330006, China
-
The First Affiliated Hospital of Ningbo University
NOT_YET_RECRUITINGNingbo, Zhejiang, 315211, China
-
The First Affiliated Hospital of USTC Anhui Provincial Hospital
NOT_YET_RECRUITINGHefei, Anhui, 230001, China
-
The First Affiliated Hospital of Wenzhou Medical University
NOT_YET_RECRUITINGWenzhou, Zhejiang, 325005, China
-
The First Affiliated Hospital of Xi'an Jiaotong University
NOT_YET_RECRUITINGXi’an, Shanxi, 710061, China
-
The First Affiliated Hospital of Xiamen University
NOT_YET_RECRUITINGXiamen, Fujian, 361003, China
-
The First Affiliated Hospital, Zhejiang University School of Medicine
RECRUITINGHangzhou, Zhejiang, 310003, China
-
The First Hospital of China Medical University
NOT_YET_RECRUITINGShenyang, Liaoning, 110001, China
-
The First Hospital of Lanzhou University
NOT_YET_RECRUITINGLanzhou, Gansu, 730000, China
-
The First Hospital of Xinjiang Medical University
NOT_YET_RECRUITINGÜrümqi, Xinjiang, 830054, China
-
The First People's Hospital of Yunnan Province
NOT_YET_RECRUITINGKunming, Yunnan, 650032, China
-
The Second Hospital of Hebei Medical Hospital
NOT_YET_RECRUITINGShijiazhuang, Hebei, 050000, China
-
The Second Xiangya Hospital of Central South University
NOT_YET_RECRUITINGChangsha, Hunan, Hunan, China
-
The Southwest Hospital of AMU
NOT_YET_RECRUITINGChongqing, Chongqing Municipality, 400038, China
-
The Third People's Hospital of Zhengzhou
NOT_YET_RECRUITINGZhengzhou, Henan, 450099, China
-
Tongji Hospital Tongji Medical College of HUST
NOT_YET_RECRUITINGWuhan, Hubei, 430030, China
-
Wuhan Union Hospital of China
NOT_YET_RECRUITINGWuhan, Hubei, 430022, China
-
Zhongda Hospital Southeast University
NOT_YET_RECRUITINGNanjing, Jiangsu, 210009, China
-
Zhongnan Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, Hubei, 430071, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can meditation tame the Long-Term side effects of a stem cell transplant?
- Could a liquid form of a Graft-Versus-Host disease drug be as effective as the pill?
- Can a cancer drug tame graft-versus-host disease when steroids fail?
- Scientists map immune battlefield in chronic GVHD tissue
- New antibody may offer safer shield against transplant complications
- Could a rheumatoid arthritis drug tame chronic GVHD and cut steroid use?