New foam aims to soothe immunotherapy skin side effects

NCT ID NCT07639840

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial tests a medicated foam called roflumilast on skin rashes caused by checkpoint inhibitor cancer drugs. Twenty adults with mild to severe rash will apply the foam daily for 16 weeks. The goal is to see if it safely reduces rash severity and improves quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

roflumilast foam 0.3%

What this could lead to

If it works, this could offer a new topical treatment to ease skin rashes from cancer immunotherapy, improving comfort without stopping cancer treatment.

What could go wrong

This is a small, early-phase trial with only 20 people, so results may not apply to everyone. The rash may not improve, or side effects could occur.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dermatitis hypersensitivity reaction disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••