New RNA vaccine targets deadliest brain cancers in kids and adults

NCT ID NCT04573140

First seen Nov 01, 2025 · Last updated May 10, 2026 · Updated 37 times

Summary

This early-phase trial tests a personalized RNA vaccine made from each patient's own tumor. It aims to train the immune system to fight aggressive brain cancers like glioblastoma and high-grade glioma in children and adults. The study focuses on safety, manufacturing feasibility, and finding the right dose in about 28 participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIGH-GRADE GLIOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UF Health

    RECRUITING

    Gainesville, Florida, 32610, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.