Simple blood test may forecast bone healing

NCT ID NCT06872775

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether RNA molecules in the blood can predict if a broken bone will heal normally, slowly, or not at all. Researchers will collect blood samples from 110 people with fractures at several time points after injury and compare the RNA test results to actual healing outcomes over 270 days. The goal is to develop a tool that helps doctors identify healing problems early.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a simple blood test that helps doctors predict whether a broken bone will heal normally or need extra treatment.

What could go wrong

This is an early observational study, not a treatment trial. The RNA test may not prove accurate enough for routine use, and results may not apply to all types of fractures.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

bone fracture

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Indiana University

    Bloomington, Indiana, 47401-3654, United States

  • University of California, Davis Medical Center

    Sacramento, California, 95817, United States

  • University of Missouri

    Columbia, Missouri, 65211-0001, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas Health Science Center at Houston

    Houston, Texas, 77030-5400, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences/Advocate Health

    Charlotte, North Carolina, 28203, United States