Simple blood test could predict broken bone healing

NCT ID NCT06872775

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 31 times

Summary

This study is testing whether RNA in the blood can accurately predict how a broken bone will heal. Researchers will collect blood samples from 110 people with fractures at several time points after injury and compare the RNA-based predictions to actual healing outcomes up to 9 months later. The goal is to develop a simple blood test that helps doctors identify early on if a fracture is likely to heal normally, slowly, or not at all.

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Contacts and locations

Locations

  • Indiana University

    Bloomington, Indiana, 47401-3654, United States

  • University of California, Davis Medical Center

    Sacramento, California, 95817, United States

  • University of Missouri

    Columbia, Missouri, 65211-0001, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Texas Health Science Center at Houston

    Houston, Texas, 77030-5400, United States

  • Vanderbilt University Medical Center

    Nashville, Tennessee, 37232, United States

  • Wake Forest University Health Sciences/Advocate Health

    Charlotte, North Carolina, 28203, United States

Conditions

Explore the condition pages connected to this study.