New drug targets Hard-to-Treat cancers with RAS mutations
NCT ID NCT05379985
First seen Nov 12, 2025 · Last updated May 05, 2026 · Updated 23 times
Summary
This study tests an experimental drug called RMC-6236 in about 754 adults with advanced solid tumors that have specific RAS gene mutations, including certain lung, colorectal, and pancreatic cancers. The main goals are to check the drug's safety and find the right dose. Participants must have good organ function and be well enough for daily activities. This is not a cure; it aims to control the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Christ Hospital Cancer Center
RECRUITINGCincinnati, Ohio, 45219, United States
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Columbia University
RECRUITINGNew York, New York, 10032, United States
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Dana Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21287, United States
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Mary Crowley Cancer Research
RECRUITINGDallas, Texas, 75230, United States
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Memorial Sloan-Kettering Cancer Center
RECRUITINGNew York, New York, 10021, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Next Oncology
RECRUITINGSan Antonio, Texas, 78229, United States
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Next Oncology Virginia
RECRUITINGFairfax, Virginia, 22031, United States
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Perlmutter Cancer Center at NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
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UC Irvine/Chao Family Comprehensive Cancer Center
RECRUITINGOrange, California, 92868, United States
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UCLA
RECRUITINGSanta Monica, California, 90404, United States
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University of Texas at Austin
RECRUITINGAustin, Texas, 78712, United States
Conditions
Explore the condition pages connected to this study.