Can a pre-treatment drug revive gout therapy in tough cases?
NCT ID NCT06186219
First seen Nov 20, 2025 · Last updated May 14, 2026 · Updated 29 times
Summary
This early-stage study tested whether giving rituximab before the standard combination of methotrexate and pegloticase can help people with severe tophaceous gout who had stopped responding to pegloticase. Only 2 participants were enrolled, and the main goal was to check safety and feasibility. The study was completed, but results are not yet reported.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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UCLA
Los Angeles, California, 90095, United States
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