New hope for kids with aggressive blood cancers: adding a targeted drug to standard chemo

NCT ID NCT01516580

Summary

This trial tested whether adding a targeted drug called rituximab to standard chemotherapy could improve survival for children and adolescents with high-risk B-cell lymphoma or leukemia. It involved 482 young patients aged 6 months to 18 years with advanced disease. The main goal was to see if the combination treatment helped patients live longer without their cancer returning or progressing.

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Contacts and locations

Locations

  • 2nd Dept. of Pediatrics Semmelweis Univ.

    Budapest, 1094, Hungary

  • Associazione Italiana di Ematologia ed Oncologia Pediatrica

    Padua, 35128, Italy

  • Children Oncology Group Operations centres

    Monrovia, Canada

  • Emma Children's Hospital

    Amsterdam, 1105 AZ, Netherlands

  • Institut de Cancérologie Gustave roussy

    Villejuif, 94805, France

  • Rectorat of Medical University

    Wroclaw, Poland

  • Sociedad Española de Hematología y Oncología Pediátricas

    Valencia, 46010, Spain

  • The University of Hong Kong (Clinical Trials Centre)

    Hong Kong, China

  • University Hospitals Leuven

    Leuven, 3000, Belgium

  • University of Birmingham

    Birmingham, United Kingdom

Conditions

Explore the condition pages connected to this study.