Can a single drug stop kidney rejection? new study investigates

NCT ID NCT01350882

Completed Disease control Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jan 11, 2026 · Last updated Apr 25, 2026 · Updated 12 times

Summary

This study tested whether the drug rituximab can help treat a type of kidney rejection called humoral acute rejection in people who had a kidney transplant within the past year. The trial included 40 adults and measured if the treatment prevented graft loss or improved kidney function by day 12. The goal was to see if adding rituximab to standard care could better control rejection and protect the transplanted kidney.

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Contacts and locations

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Locations

Hospital

Grenoble, La Tronche, 38700, France
Hospital

Angers, 49933, France
Hospital

Brest, 29609, France
Hospital

Caen, 14033, France
Hospital

Rennes, 35033, France
Hospital Bicêtre

Paris, Le Kremlin Bicêtre, 94275, France
Hospital Bocage

Dijon, 21000, France
Hospital Bois-Guillaume

Rouen, 76231, France
Hospital Bretonneau

Tours, 37044, France
Hospital Calmette

Lille, 59037, France
Hospital Civil

Strasbourg, 67091, France
Hospital Conception

Marseille, 13385, France
Hospital Dupuytren

Limoges, 87042, France
Hospital Edouard Herriot

Lyon, 69437, France
Hospital Gabriel Montpied

Clermont-Ferrand, 63003, France
Hospital Henri Mondor

Paris, Créteil, 94010, France
Hospital Hôtel Dieu

Nantes, 44093, France
Hospital Lapeyronie

Montpellier, 34295, France
Hospital Lyon Sud

Lyon, Pierre-Benite, 69495, France
Hospital Maison Blanche

Reims, 51092, France
Hospital Milétrie Jean Bernard

Poitiers, 86021, France
Hospital Necker

Paris, 75743, France
Hospital Nord

Saint-Etienne, Saint Priez-en-Jarez, 42227, France
Hospital Pasteur

Nice, 06000, France
Hospital Pellegrin

Bordeaux, 33076, France
Hospital Pitié-Salpêtrière

Paris, 75651, France
Hospital Saint Louis

Paris, 75000, France
Hospital Saint-Jacques

Besançon, 25030, France
Hospital Sud

Amiens, 80054, France
Hospital Tenon

Paris, 75020, France

Conditions

Explore the condition pages connected to this study.

HUMORAL REJECTION IN KIDNEY TRANSPLANTATION