New combo therapy shows promise for kids with aggressive blood cancers
NCT ID NCT01516580
First seen Feb 28, 2026 · Last updated May 09, 2026 · Updated 5 times
Summary
This study tested whether adding 6 doses of rituximab (a targeted antibody) to standard chemotherapy improves outcomes for 482 children and teens with advanced B-cell non-Hodgkin lymphoma or B-cell leukemia. Participants were aged 6 months to 18 years with high-risk disease. The main goal was to see if the combination lengthened the time without cancer returning or other serious events.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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2nd Dept. of Pediatrics Semmelweis Univ.
Budapest, 1094, Hungary
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Associazione Italiana di Ematologia ed Oncologia Pediatrica
Padova, 35128, Italy
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Children Oncology Group Operations centres
Monrovia, Canada
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Emma Children's Hospital
Amsterdam, 1105 AZ, Netherlands
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Institut de Cancérologie Gustave roussy
Villejuif, 94805, France
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Rectorat of Medical University
Wroclaw, Poland
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Sociedad Española de Hematología y Oncología Pediátricas
Valencia, 46010, Spain
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The University of Hong Kong (Clinical Trials Centre)
Hong Kong, China
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University Hospitals Leuven
Leuven, 3000, Belgium
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University of Birmingham
Birmingham, United Kingdom
Conditions
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