Smart dosing of rituximab may prevent relapse in rare vasculitis

NCT ID NCT01731561

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 28 times

Summary

This study tested whether giving rituximab based on blood markers (ANCA and CD19) works as well as giving it on a fixed schedule to prevent relapses in people with ANCA-associated vasculitis. 166 adults in remission were randomly assigned to one of two rituximab plans and followed for 28 months. The goal was to see which approach better prevents disease flares while keeping side effects low.

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Contacts and locations

Locations

  • Cochin Hospital

    Paris, 75014, France

Conditions

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