Can a B-Cell blocker shrink prostate tumors before surgery?
NCT ID NCT01804712
First seen Mar 25, 2026 · Last updated May 16, 2026 · Updated 9 times
Summary
This early-phase study tested whether giving rituximab (a drug that depletes B cells) before prostate removal surgery could reduce B cell levels in the tumor. Eight men with high-risk prostate cancer received four weekly doses before their scheduled prostatectomy. The main goal was to measure changes in B cell density in the removed prostate tissue, not to treat the cancer directly.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Moores UCSD Cancer Center
La Jolla, California, 92093-0698, United States
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