Matching AML therapy to genetics and fitness boosts survival in seniors

NCT ID NCT03226418

First seen Nov 06, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This study looked at whether tailoring chemotherapy for older adults (60+) with acute myeloid leukemia (AML) based on their genetic profile and overall health can improve outcomes. 75 participants received either standard intensive or milder therapy based on these factors. The goal was to see if this personalized approach could increase remission rates and reduce early death, while also tracking quality of life and survival over two years.

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Contacts and locations

Locations

  • University of Nebraska Medical Center

    Omaha, Nebraska, 68198, United States

Conditions

Explore the condition pages connected to this study.